The Grothendieck spectral sequence computes the right derived functors of a composition of left exact functors
and
between Abelian categories. Assume
and
have enough injectives
and that
for every injective object
of
and every
.
For an object
of
,
it has
with , and induces a finite filtration on each object
(The Stacks Project Authors 2026). Here left exact
means preserving exactness at the first two places of a short exact
sequence. An object
is an injective object
when the hom functor
is exact, and enough injectives
means that every object embeds in such an
. The Leray spectral
sequence is a sheaf-theoretic example.