The isomorphism fixes the ground field. Geometrically, it asks whether every hypersurface embedding of affine -space in affine -space can be carried to a coordinate hyperplane by an ambient
polynomial automorphism.
Gupta, N. "The Zariski Cancellation Problem and Related Problems in Affine Algebraic Geometry." In Proc. International Congress of
Mathematicians 2022, Vol. 3: Sections 1-4 (Ed. D. Beliaev and S. Smirnov).
Berlin, Germany: EMS Press, pp. 1578-1598, 2023. https://doi.org/10.4171/ICM2022/151.