Define
(1)
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(2)
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(3)
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where , , , and are vertices of a graph and is the graph distance between vertices and . Then a connected Ptolemaic graph is a graph such that a weak form of the triangle inequality
(4)
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(5)
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(6)
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holds for any four vertices (Kay and Chartrand 1965, Howorka 1981).
The numbers of connected Ptolemaic graphs on , 2, ... vertices are 1, 1, 2, 5, 14, 47, 170, 676, 2834, 12471, 56675, 264906, ... (OEIS A287888).
The definition can be extended to disconnected graphs by allowing 4-tuples of points in each connected component to satisfy these conditions separately (Bahrani and Lumbroso 2016).
A connected graph is Ptolemaic iff is it distance-heritary and chordal (Howorka 1981, Bahrani and Lumbroso 2016). Ptolemaic graphs are perfect.
Classes of graphs that are Ptolemaic include block graphs.